Previous Projects  

2014Assessment of Structural and Functional Knee Joint Degradation During Modeled Spaceflight
Jeffrey S. Willey, Ph.D.

2014Developing Novel,Targeted Countermeasures to Reduce Oxidative Stress and Skeletal Muscle Atrophy During Microgravity
James M. Kuczmarski, Ph.D.

2013Contribution of the Vestibular and Sympathetic Nervous Systems to Space-Induced Bone Loss (Postdoctoral Fellowship)
Guillaume Vignaux, Ph.D.

2013Monitoring Bone Health by Daily Load Stimulus Measurement During Lunar Missions
Peter R. Cavanagh, Ph.D., D.Sc.

2012Maintaining Musculoskeletal Health in the Lunar Environment
Susan A. Bloomfield, Ph.D.

2012An Integrated Musculoskeletal Countermeasure Battery for Long-Duration Lunar Missions
Thomas F. Lang, Ph.D.

2012Integrated Endurance and Resistance Exercise Countermeasures Using a Gravity-Independent Training Device
Gregory R. Adams, Ph.D.

2011Enhancing the Efficacy of Musculoskeletal Countermeasures Using Computer Simulation (Postdoctoral Fellowship)
Andrea M. Hanson, Ph.D.

2011Molecular Mechanisms that Impact Transcription of Myosin Genes in Human Skeletal Muscle in Response to Unloading: Role of Resistance Exercise (Postdoctoral Fellowship)
Clay E. Pandorf, Ph.D.

2011Interaction Between IGF-1 and Integrin Signaling in the Response of Bone to Mechanical Load (Postdoctoral Fellowship)
Takuo Kubota, M.D., Ph.D.

2011Space Radiation and Bone Loss: Lunar Outpost Mission-Critical Scenarios and Countermeasures
Ted A. Bateman, Ph.D.

2011Bone Formation through Biomineralization and Bioengineering (Postdoctoral Fellowship)
Ronke M. Olabisi, Ph.D.

2010A Combinatorial Approach of Exercise and Myostatin Inhibition to Enhance Compromised Bone (Postdoctoral Fellowship)
Stephanie M. Carleton, Ph.D.

2010Effects of Abnormal Loading on Tibiofemoral Articular Cartilage Composition (Postdoctoral Fellowship)
Richard B. Souza, Ph.D.

2010Radiation Effects on Bone Tissue and Cells in Reduced Gravity (Postdoctoral Fellowship)
Jeffrey S. Willey, Ph.D.

2009Redox Modulation of Skeletal Muscle Function in Microgravity
Michael B. Reid, Ph.D.

2009A Quantitative Test of On-Orbit Exercise Countermeasures for Bone Demineralization Using a Bedrest Analog
Peter R. Cavanagh, Ph.D., D.Sc.

2009Recovery of IGF-1 Signaling in Bone by Skeletal Reloading (Postdoctoral Fellowship)
Roger Long, M.D.

2008Foot Reaction Forces During Simulated ISS Exercise Countermeasures
Peter R. Cavanagh, Ph.D., D.Sc.

2008Bone Recovery Potential after Bisphosphonate and PTH Treatment of Disuse Osteoporosis
Mitchell B. Schaffler, Ph.D.

2008Examination of Anti-Resorptive and Anabolic Treatments/Stimuli on Unloading-Induced Osteoporosis
Ted A. Bateman, Ph.D.

2008Hypergravity Resistance Training: Countermeasure to Microgravity
Vincent J. Caiozzo, Ph.D.

2008Increasing the Efficiency of Exercise Countermeasures for Bone Loss
Susan A. Bloomfield, Ph.D.

2008Force Regulation as a Countermeasure to Muscle Atrophy
Kenneth M. Baldwin, Ph.D.

2007The Activation of Protein Breakdown in Muscle Upon Unloading and Possible Countermeasures
Alfred L. Goldberg, Ph.D.

2007Effects of Simulated Weightlessness on the Repair of Lower-Limb Bone Fractures and on the Number of Bone-Derived Stem Cells
Ronald J. Midura, Ph.D.

2006The Use of Aspirin and Other NSAIDs to Ameliorate Muscle Atropy Due to Simulated Weightlessness (Postdoctoral Fellowship)
Andrew Judge, Ph.D.

2006Receptor Countermeasures to Bone Loss in Microgravity
Carolyn L. Smith, Ph.D.

2005Therapeutic Modulation of Systemic Glucose-Dependent Insulinotropic Peptide Levels to Counteract Microgravity-Induced Bone Loss
Carlos M. Isales, M.D.

2005Prevention of Microgravity-Induced Stone Risk by KMgCitrate
Joseph E. Zerwekh, Ph.D.

2005Defining and Preventing Bone Loss: A Microgravity Model
Jay R. Shapiro, M.D.

2005Redox Modulation of Muscle Function in Microgravity
Michael B. Reid, Ph.D.

2005Ultrasonic Assessment of Anisotropic Mechanical Properties of Cancellous Bone after Disuse with and without Anti-Resorptive Therapy (Postdoctoral Fellowship)
Luis Cardoso Landa, Ph.D.

2005Genomics of Human Skeletal Muscle During Bed Rest and Exercise
Marc T. Hamilton, Ph.D.

2005In Vivo Stress-Strain Dynamics in Human Muscle
Shantanu Sinha, Ph.D.

2005Cell and Molecular Biomechanics: Cardiac & Skeletal Muscle
P. Bryant Chase, Ph.D.

2004Calpains in Simulated Microgravity-Induced Muscle Atrophy
Parker B. Antin, Ph.D.

2004Ca+2 Homeostatis and Muscle Phenotype: Role of Cellular Energetics
Robert W. Wiseman, Ph.D.

2004Bone and Muscle Recovery from Simulated Microgravity
Susan A. Bloomfield, Ph.D.

2004Gene Expression Profiling of Unloaded Skeletal Muscle
Susan C. Kandarian, Ph.D.

2004Effect of Microgravity on Fracture Healing/Ultrasound as a Possible Countermeasure
Mark E. Bolander, M.D.

2004Integrating Human Muscle Energetics and Mechanics
Martin J. Kushmerick, M.D., Ph.D.

2004Resorption Suppression and Bone Health in Disuse
Mitchell B. Schaffler, Ph.D.

2004Role of Muscle Loading on Mechanisms of Protein Translation and the Impact on Unloading-Induced Atrophy
Kenneth M. Baldwin, Ph.D.

2004The Activation of Protein Breakdown in Muscle Upon Unloading and Possible Countermeasures
Alfred L. Goldberg, Ph.D.

2004Leptin as a Regulator of Bone Formation in Microgravity
Gerard Karsenty, M.D., Ph.D.

2004Receptor Countermeasures to Bone Loss in Microgravity
Carolyn L. Smith, Ph.D.

2004A Biomechanical Countermeasure for Disuse Osteopenia
Clinton Rubin, Ph.D.

2000Motoneuron Influences on Muscle Atrophy in Simulated Microgravity Induced Muscle Atrophy
Dennis R. Mosier, M.D., Ph.D.

2000Skeletal Structural Consequences of Reduced Gravity Environments
Christopher B. Ruff, Ph.D.

2000Novel Receptor-Based Countermeasures to Microgravity-Induced Bone Loss
Bert W. O'Malley, M.D.

2000Pharmacological Inhibitors of the Proteosome in Atrophying Muscles (Also Kenneth Baldwin, Ph.D., UC Irvine, Effects of Unloading on Myosin Content and Isoform Specific Regulation in Skeletal Muscle)
Alfred L. Goldberg, Ph.D.

2000Molecular Signaling in Muscle Plasticity
Henry F. Epstein, M.D.

2000The Effects of Partial Mechanical Loading and Ibandronate on Skeletal Tissues in the Adult Rat Hindquarter Suspension Model for Microgravity
Lester W. Schultheis, M.D.

2000Activity Dependent Signal Transduction in Skeletal Muscle
Susan L. Hamilton, Ph.D.

2000Bone Blood Flow During Simulated Microgravity: Physiological and Molecular Mechanisms
Susan A. Bloomfield, Ph.D.

2000Molecular Mechanisms Regulating Muscle Fiber Composition Under Microgravity
Nadia A. Rosenthal, Ph.D.

2000GH/IGF-I Transgene Expression on Muscle Homeostasis
Robert J. Schwartz, Ph.D.

Extent, Causes and Countermeasures of Impaired Fracture Healing in Hypogravity
Ronald J. Midura, Ph.D.

Pharmaceutical Countermeasure Effects on Tissue-Level Quality of Immobilized Bone (Postdoctoral Fellowship)
Devendra Bajaj, Ph.D.

Regenerative Wound Dressing for Improved Healing in Space
Abram D. Janis

An Integrated Low-Volume Nutritional Countermeasure to Maintain Muscle Mass and Function During Space Exploration
Douglas Paddon-Jones, Ph.D.