
NSBRI encourages and expects its funded investigators to publish findings of their research in scholarly, peer-reviewed journals. Below is a comprehensive list of publications for the Smart Medical Systems and Technology Team since the Institute's inception in 1997. Bailey MR, Khokhlova VA, Sapozhnikov OA, Kargl SG, Crum LA. Physical mechanisms of the therapeutic effect of ultrasound. Acoustical Physics 49(4):437-464, 2003. Article abstract Barnes SL, Branson R, Gallo LA, Beck G, Johannigman JA. En-route care in the air: Snapshot of mechanical ventilation at 37,000 feet. J Trauma. 2008 Feb;64(2 Suppl):S129-34; discussion S134-5. PMID: 18376155 Beck G, Melton S, Dulchavsky SA. Critical care medicine in space. Aviat Space Environ Med. 2005 Feb;76(2):163. PMID: 15742836 Benninger MS, McFarlin K, Hamilton DR, Rubinfeld I, Sargsyan AE, Melton SM, Mohyi M, Dulchavsky SA. Ultrasound evaluation of sinus fluid levels in swine during microgravity conditions. Aviat Space Environ Med. 2009 Dec;80(12):1063-5. PMID: 20027856 Bessonova OV, Khokhlova VA, Bailey MR, Canney MS, Crum LA. Focusing of high intensity ultrasound beams and ultimate values of shock wave parameters. Acoustical Physics. 2009 Oct; 55(4-5): 463-473. PMID: 20161349 Bessonova OV, Khokhlova VA, Canney MS, Bailey MR, Crum LA. A derating method for therapeutic applications of high intensity focused ultrasound. Acoust Phys. 2010 Jan 1;56(3):354-363. PMID: 20582159 Boas DA, Strangman G, Culver JP, Hoge RD, Jasdzewski G, Poldrack RA, Rosen BR, Mandeville JB. Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy? Phys Med Biol. 2003 Aug 7;48(15):2405-18. PMID: 12953906 Buckey JC, Knaus DA, Alvarenga DL, Kenton MA, Magari PJ. Dual-frequency ultrasound for detecting and sizing bubbles. Acta Astronaut. 2005 May-Jun;56(9-12):1041-7. PMID: 15835064 Burgess S, Zderic V, Vaezy S. Image-guided acoustic hemostasis for treatment of hidden liver injuries. Ultrasound Med Biol. 2007 Jan;33:113-119. PMID: 17189053 Busa B, Miller LM, Rubin CT, Qin YX, Judex S. Rapid establishment of chemical and mechanical properties during lamellar bone formation. Calcif Tissue Int. 2005 Dec;77(6):386-94. PMID: 16362460 Canney MS, Bailey MR, Crum LA, Khokhlova VA, Sapozhnikov OA. Acoustic characterization of high intensity focused ultrasound fields: A combined measurement and modeling approach. J Acoust Soc Am. 2008 Oct;124(4):2406-20. PMID: 19062878 Canney MS, Khokhlova VA, Bessonova OV, Bailey MR, Crum LA. Shock-induced heating and millisecond boiling in gels and tissue due to high intensity focused ultrasound. Ultrasound Med Biol. 2010 Feb;36(2):250-67. PMID: 20018433 Charles, Jr., H. K. Electronic instrument development for applications in space biomedicine and astronaut health. Advancing Microelectronics 26(6):6-9, 2002. Charles HK Jr, Beck TJ, Feldmesser HS, Magee TC, Spisz TS, Pisacane VL. Precision bone and muscle loss measurements by advanced, multiple projection DEXA (AMPDXA) techniques for spaceflight applications. Acta Astronaut. 2001 Aug-Nov;49(3-10):447-50. PMID: 11669130 Davies PF. Molecular phenotypes of atherosclerosis: fingering the perpetrators. Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1746-7. PMID: 15472136 Dulchavsky SA, Sargsyan AE, Garcia KM, Melton SL, Ebert D and Hamilton DR. Intuitive ultrasonography for autonomous medical care in limited-resource environments. Acta Astro., 68 (9-10): 1594-1607, 2011. Foale CM, Kaleri AY, Sargsyan AE, Hamilton DR, Melton S, Martin D, Dulchavsky SA. Diagnostic instrumentation aboard ISS: just-in-time training for non-physician crewmembers. Aviat Space Environ Med. 2005 Jun;76(6):594-8. PMID: 15945407 Greaby R, Zderic V, Vaezy S. Pulsatile flow phantom for ultrasound image-guided HIFU treatment of vascular injuries. Ultrasound Med Biol. 2007 Aug;33(8):1269-76. PMID: 17466441 Grey M, Goldsten J, Maurer R, Roth D, Zeitlin C. Data acquisition for the Combined Ion and Neutron Spectrometer (CINS). Nucl Instrum Methods Phys Res B. 2009 Jan;267(1):139-43. Article abstract Hamilton DR, Alferova IV, Sargsyan AE, Fincke E., Magnus SH, Lonchakov YV, Dulchavsky SA, Ebert D, Garcia K, Martin D, Matveev VP, Voronkov YI, Melton SL, Bogomolov VV, Duncan JM. Right ventricular tissue Doppler assessment in space during circulating volume modification using the Braslet device. Acta Astro., 68 (9-10): 1501-1508, 2011. Jasdzewski G, Strangman G, Wagner J, Kwong KK, Poldrack RA, Boas DA. Differences in the hemodynamic response to event-related motor and visual paradigms as measured by near-infrared spectroscopy. Neuroimage. 2003 Sep;20(1):479-88. PMID: 14527608 Khokhlova TD, Canney MS, Lee D, Marro KI, Crum LA, Khokhlova VA, Bailey MR. Magnetic resonance imaging of boiling induced by high intensity focused ultrasound. J Acoust Soc Am. 2009 Apr;125(4):2420-31. PMID: 19354416 Kinnison JD, Maurer RH, Roth DR, Haight RC. High-energy neutron spectroscopy with thick silicon detectors. Radiat Res. 2003 Feb;159(2):154-60. PMID: 12537520 Kucewicz JC, Bailey MR, Kaczkowski PJ, Carter SJ. Focused ultrasound: concept for automated transcutaneous control of hemorrhage in austere settings. Aviat Space Environ Med. 2009 Apr;80(4):391-4. PMID: 19378911 Kwon D, Bouffard JA, van Holsbeeck M, Sargsyan AE, Hamilton DR, Melton SL, Dulchavsky SA. Battling fire and ice: remote guidance ultrasound to diagnose injury on the International Space Station and the ice rink. Am J Surg. 2007 Mar;193(3):417-20. PMID: 17320547 Lafon C, Khokhlova VA, Kaczkowski PJ, Bailey MR, Sapozhnikov OA, Crum LA. Use of a bovine eye lens for observation of HIFU-induced lesions in real-time. Ultrasound Med Biol. 2006 Nov;32(11):1731-41. PMID: 17112959 Lafon C, Zderic V, Noble ML, Yuen JC, Kaczkowski PJ, Sapozhnikov OA, Chavrier F, Crum LA, Vaezy S. Gel phantom for use in high-intensity focused ultrasound dosimetry. Ultrasound Med Biol. 2005 Oct;31(10):1383-9. PMID: 16223642 Lam H, Qin YX. The effects of frequency-dependent dynamic muscle stimulation on inhibition of trabecular bone loss in a disuse model. Bone. 2008 Dec;43(6):1093-100. PMID: 18757047 Li N, Ho CM. Patterning functional proteins with high selectivity for biosensor applications. J Assoc Lab Automation. 2008 Aug;13(4):237-42. Full article Li N, Ho CM. Photolithographic patterning of organosilane monolayer for generating large area two-dimensional B lymphocyte arrays. Lab Chip. 2008 Dec;8(12):2105-12. PMID: 19023473 Lillehoj PB, Tsutsui H, Valamehr B, Wu H, Ho CM. Continuous sorting of heterogeneous-sized embryoid bodies. Lab Chip. 2010 Jul 7;10(13):1678-82. PMID: 20376391 Lin W, Xia Y, Qin YX. Characterization of the trabecular bone structure using frequency modulated ultrasound pulse. J Acoust Soc Am. 2009 Jun;125(6):4071-7. PMID: 19507988 Luo W, Zderic V, Carter S, Crum L, Vaezy S. Detection of bleeding in injured femoral arteries with contrast-enhanced sonography. J Ultrasound Med. 2006 Sep;25(9):1169-77. PMID: 16929018 Maurer RH, Charles HK Jr, Pisacane VL. Advances in space technology: The NSBRI technology development team. Radiat Prot Dosimetry. 2002;100(1-4):479-87. PMID: 12382926 Maurer RH, Roth DR, Kinnison JD, Goldsten JO, Gold RE, Fainchtein R. Mars Neutron Energy Spectrometer (MANES): an instrument for the Mars 2003 Lander. Acta Astronaut. 2003 Jan-Mar;52(2-6):405-10. PMID: 12674102 Maurer RH, Zeitlin CJ, Haggerty DK, Roth DR, Goldsten JO. Compact ion and neutron spectrometer (CINS) for space applications. IEEE Nuclear Science Symposium Conference Record N14-48:428-432, 2005. Full article McFarlin K, Sargsyan AE, Melton S, Hamilton DR, Dulchavsky SA. A surgeon's guide to the universe. Surgery. 2006 May;139(5):587-90. PMID: 16701089 Mercado-Young R, Martin DS, Caine T, O'Connell K, Garcia K, Sargsyan A, Platts S, Dulchavsky SA. Virtual guidance: A new technique to empower point-of-care ultrasound in remote or extreme environments. Crit Ultrasound J. 2010 Jul;2(1):19-24. Full article Mittra E, Akella S, Qin YX. The effects of embedding material, loading rate and magnitude, and penetration depth in nanoindentation of trabecular bone. J Biomed Mater Res A. 2006 Oct;79(1):86-93. PMID: 16758456 Mittra E, Rubin C, Gruber B, Qin YX. Evaluation of trabecular mechanical and microstructural properties in human calcaneal bone of advanced age using mechanical testing, microCT, and DXA. J Biomech. 2008;41(2):368-75. PMID: 17953972 Mittra E, Rubin C, Qin Y. Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone. J Biomech. 2005 Jun;38(6):1229-37. PMID: 15863107 Mortimer AJ, DeBakey ME, Gerzer R, Hansen R, Sutton J, Neiman SN. Life science research in space brings health on Earth. Acta Astronaut. 2004 Jun;54(11-12):805-12. PMID: 15793934 Otto C, Comtois JM, Sargsyan A, Dulchavsky A, Rubinfeld I, Dulchavsky S. The Martian chronicles: Remotely guided diagnosis and treatment in the Arctic Circle. Surg Endosc. 2010 Sep;24(9):2170-7. PMID: 20229213 Ouellette AL, Li JJ, Cooper DE, Ricco AJ, Kovacs GT. Evolving point-of-care diagnostics using up-converting phosphor bioanalytical systems. Anal Chem. 2009 May 1;81(9):3216-21. PMID: 19368339 Owen NR, Bailey MR, Crum LA, Sapozhnikov OA, Trusov LA. The use of resonant scattering to identify stone fracture in shock wave lithotripsy. J Acoust Soc Am. 2007 Jan;121(1):EL41-7. PMID: 17297825 Owen NR, Bailey MR, Hossack J, Crum LA. A method to synchronize high-intensity, focused ultrasound with an arbitrary ultrasound imager. IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Mar;53(3):645-50. PMID: 16555774 Paek B, Foley J, Zderic V, Starr F, Shields LE, Vaezy S. Selective reduction of multifetal pregnancy using high-intensity focused ultrasound in the rabbit model. Ultrasound Obstet Gynecol. 2005 Sep;26(3):267-70. PMID: 16116566 Passerini AG, Polacek DC, Shi C, Francesco NM, Manduchi E, Grant GR, Pritchard WF, Powell S, Chang GY, Stoeckert CJ Jr, Davies PF. Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2482-7. PMID: 14983035 Qin YX, Lam H, Ferreri S, Rubin C. Dynamic skeletal muscle stimulation and its potential in bone adaptation. J Musculoskelet Neuronal Interact. 2010 Mar;10(1):12-24. PMID: 20190376 Rabkin BA, Zderic V, Crum LA, Vaezy S. Biological and physical mechanisms of HIFU-induced hyperecho in ultrasound images. Ultrasound Med Biol. 2006 Nov;32:1721-1729. PMID: 17112958 Sapozhnikov OA, Maxwell AD, MacConaghy B, Bailey MR. A mechanistic analysis of stone fracture in lithotripsy. J Acoust Soc Am. 2007 Feb;121(2):1190-1202. PMID: 17348540 Sargsyan AE, Dulchavsky AG, Adams J, Melton S, Hamilton DR, Dulchavsky SA. Ultrasound detection of simulated intra-ocular foreign bodies by minimally trained personnel. Aviat Space Environ Med. 2008 Jan;79(1):58-61. PMID: 18225781 Sargsyan AE, Hamilton DR, Melton SL, Amponsah D, Marshall NE, Dulchavsky SA. Ultrasonic evaluation of pupillary light reflex. Crit Ultrasound J. 2009 Oct; 1:53–57. Full article Shah A, Owen NR, Lu W, Cunitz BW, Kaczkowski PJ, Harper JD, Bailey MR, Crum LA. Novel ultrasound method to reposition kidney stones. Urol Res. 2010 Oct 22. [Epub ahead of print] PMID: 20967437 Soller BR, Idwasi PO, Balaguer J, Levin S, Simsir SA, Vander Salm TJ, Collette H, Heard SO. Noninvasive, near infrared spectroscopic-measured muscle pH and PO2 indicate tissue perfusion for cardiac surgical patients on cardiopulmonary bypass. Crit Care Med. 2003 Sep;31(9):2324-31. PMID: 14501963 Soller BR, Yang Y, Soyemi OO, Ryan KL, Rickards CA, Walz JM, Heard SO, Convertino VA. Noninvasively determined muscle oxygen saturation is an early indicator of central hypovolemia in humans. J Appl Physiol. 2008 Feb 8;104:475-481. PMID: 18006869 Sorensen MD, Shah AR, Canney MS, Sapozhnikov OA, Teichman JM, Bailey MR. Ureteroscopic ultrasound technology to size kidney stone fragments: Proof of principle using a miniaturized probe in a porcine model. J Endourol. 2010 Jun;24(6):939-42. PMID: 20136398 Sorensen MD, Teichman JM, Bailey MR. Proof of principle of a prototype ultrasound technology to size stone fragments during ureteroscopy. J Endouro. 2009 Jul;23(7):1161-4. PMID: 19538061 Soyemi OO, Landry MR, Yang Y, Idwasi PO, Soller BR. Skin color correction for tissue spectroscopy: demonstration of a novel approach with tissue-mimicking phantoms. Appl Spectrosc. 2005 Feb;59(2):237-44. PMID: 15720765 Strangman G, Boas DA, Sutton JP. Non-invasive neuroimaging using near-infrared light. Biol Psychiatry. 2002 Oct 1;52(7):679-93. PMID: 12372658 Strauss MM, Makris N, Aharon I, Vangel MG, Goodman J, Kennedy DN, Gasic GP, Breiter HC. fMRI of sensitization to angry faces. Neuroimage. 2005 Jun;26(2):389-413. PMID: 15907298 Sutton JP, Jamieson IM. Reconfigurable networking for coordinated multi-agent sensing and communications. Inf Sci (Ny). 2002 Dec;148(1-4):103-11. PMID: 14983838 Vaezy S, Zderic V, Karmy-Jones R, Jurkovich GJ, Cornejo C, Martin RW. Hemostasis and sealing of air leaks in the lung using high-intensity focused ultrasound. J Trauma. 2007 Jun;62(6):1390-5. PMID: 17563654 Ward KR, Tiba MH, Ryan KL, Filho IP, Rickards CA, Witten T, Soller BR, Ludwig DA, Convertino VA. Oxygen transport characterization of a human model of progressive hemorrhage. Resuscitation. 2010 Aug;81(8):987-93. PMID: 20418009 Wilbur JC, Phillips SD, Donoghue TG, Alvarenga DL, Knaus DA, Magari PJ, Buckey JC. Signals consistent with microbubbles detected in legs of normal human subjects after exercise. J Appl Physiol. 2010 Feb;108(2):238-9. PMID: 19875715 Wroe AJ, Rosenfeld AB, Cornelius IM, Prokopovich D, Reinhard M, Schulte R, Bashkirov V. Silicon microdosimetry in heterogeneous materials: simulation and experiment. IEEE Trans Nuc Sci. December 2006, 53(6), 1, 3738-3744. Full article Xia Y, Lin W, Qin Y. The influence of cortical end-plate on broadband ultrasound attenuation measurements at the human calcaneus using scanning confocal ultrasound. J Acoust Soc Am, 2005 Sep;118(3 Pt 1):1801-7. PMID: 16240838 Xia Y, Lin W, Qin YX. Bone surface topology mapping and its role in trabecular bone quality assessment using scanning confocal ultrasound. Osteoporos Int. 2007 Jul;18(7):905-13. PMID: 17361323 Yang Y, Landry MR, Soyemi OO, Shear MA, Anunciacion DS, Soller BR. Simultaneous correction of the influence of skin color and fat on tissue spectroscopy by use of a two-distance fiber-optic probe and orthogonalization technique. Opt Lett. 2005 Sep 1;30(17):2269-71. PMID: 16190440 Yang Y, Shoer L, Soyemi OO, Landry MR, Soller BR. Removal of analyte-irrelevant variations in near-infrared tissue spectra. Appl Spectrosc. 2006 Sep;60(9):1070-7. PMID: 17002833 Yang Y, Soyemi OO, Landry MR, Soller BR. Influence of a fat layer on the near infrared spectra of human muscle: quantitative analysis based on two-layered Monte Carlo simulations and phantom experiments. Opt Express. 2005 Mar 7;13(5):1570-9. PMID: 16044624 Yang Y, Soyemi OO, Landry MR, Soller BR. Noninvasive in vivo measurement of venous blood pH during exercise using near-infrared reflectance spectroscopy. Appl Spectrosc. 2007 Feb;61(2):223-229. PMID: 17331316 Yang Y, Soyemi OO, Scott PJ, Landry MR, Lee SM, Stroud L, Soller BR. Quantitative measurement of muscle oxygen saturation without influence from skin and fat using continuous-wave near infrared spectroscopy. Opt Express. 2007 Oct 17;15(21):13715-30. PMID: 19550643 Zderic V, Brayman AA, Sharar SR, Crum LA, Vaezy S. Microbubble-enhanced hemorrhage control with high intensity focused ultrasound. Ultrasonics. 2006 Dec;45(1-4):113-120. PMID: 16949630 Zderic V, Foley J, Luo W, Vaezy S. Prevention of post-focal thermal damage by formation of bubbles at the focus during high intensity focused ultrasound therapy. Med Phys. 2008 Oct;35(10):4292-9. PMID: 18975674 Zderic V, Keshavarzi A, Noble ML, Paun M, Sharar SR, Crum LA, Martin RW, Vaezy S. Hemorrhage control in arteries using high-intensity focused ultrasound: a survival study. Ultrasonics. 2006 Jan;44(1):46-53. PMID: 16176829 Zderic V, O'Keefe GE, Foley JL, Vaezy S. Resection of abdominal solid organs using high-intensity focused ultrasound. Ultrasound Med Biol. 2007 Aug;33(8):1251-8. PMID: 17498864 Zeitlin C, Maurer R, Roth D, Goldsten J, Grey M. Development and evaluation of the Combined Ion and Neutron Spectrometer (CINS). Nuclear Instrum Meth Phys Res Sec B: Beam Interactions with Materials and Atoms 2009 Jan;267(1):125-38. Article abstract Zheng S, Lin JC-H, Kasdan HL, Tai YC. Fluorescent labeling, sensing, and differentiation of leukocytes from undiluted whole blood samples. Sens Actuators B Chem. 2008 Jun;132:558-567. Full article Zheng S, Liu M, Tai YC. Micro coulter counters with platinum black electroplated electrodes for human blood cell sensing. Biomed Microdevices. 2008 Apr;10(2):221-31. PMID: 17876707 Zheng S, Liu JQ, Tai YC. Streamline based microfluidic device for erythrocytes and leukocytes separation. J MEMS. 2008 Aug;17(4):1029-1038. Full article Zheng S, Nandra MS, Shih CY, Li W, Tai YC. Resonance impedance sensing of human blood cells. Sens Actuators A: Phys 2008 Jul-Aug;145-146:29-36. Full article Zou F, Jin C, Ross RR, Soller BR. Investigation of spectral interferences on the accuracy of broadband CW-NIRS tissue SO₂ determination. Biomedical Optics Express. 2010 Aug;(1)3:748-761. Article |