Team Publications


NSBRI encourages and expects its funded investigators to publish findings of their research in scholarly, peer-reviewed journals. Below is a comprehensive list of publications for the Radiation Effects Team since the Institute's inception in 1997.

Acharya MM, Lan ML, Kan VH, Patel NH, Giedzinski E, Tseng BP, Limoli CL. Consequences of ionizing radiation-induced damage in human neural stem cells. Free Radic Biol Med. 2010 Sep 6. [Epub ahead of print]. PMID: 20826207

Aviles H, Belay T, Fountain K, Vance M, Sonnenfeld G.  Increased susceptibility to Pseudomonas aeruginosa infection under hindlimb-unloading conditions.  J Appl Physiol. 2003 Jul;95(1):73-80. 
PMID: 12626488

Aviles H, Belay T, Fountain K, Vance M, Sun B, Sonnenfeld G.  Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infection in mice in the hindlimb-unloading model of spaceflight conditions.  J Appl Physiol. 2003 Aug;95(2):491-6.  PMID: 12692142

Aviles H, Belay T, Vance M, Sonnenfeld G. Effects of space flight conditions on the function of the immune system and catecholamine production simulated in a rodent model of hindlimb unloading.  Neuroimmunomodulation. 2005;12(3):173-81.  PMID: 15905626

Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G.  Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of space flight conditions.  J Appl Physiol. 2004 Oct;97(4):1437-44.  PMID: 15194672

Balan S, Murphy J, Galaev I, Kumar A, Fox GE, Mattiasson B, Willson RC.  Metal chelate affinity precipitation of RNA and purification of plasmid DNA.  Biotechnol Lett. 2003 Jul;25(13):1111-6.  PMID: 12889823

Belay T, Aviles H, Vance M, Fountain K, Sonnenfeld G.  Catecholamines and in vitro growth of pathogenic bacteria: enhancement of growth varies greatly among bacterial species.  Life Sci. 2003 Aug 8;73(12):1527-35.  PMID: 12865092

Belay T, Aviles H, Vance M, Fountain K, Sonnenfeld G.  Effects of the hindlimb-unloading model of spaceflight conditions on resistance on mice to infection with Klebsiella pneumoniae.  J Allergy Clin Immunol. 2002 Aug;110(2):262-8.  PMID: 12170267

Belay T, Sonnenfeld G.  Differential effects of catecholamines on in vitro growth of pathogenic bacteria.  Life Sci. 2002 Jun 14;71(4):447-56.  PMID: 12044844

Bennett PV, Cintron NS, Gros L, Laval J, Sutherland BM.  Are endogenous clustered DNA damages induced in human cells?  Free Radic Biol Med. 2004 Aug 15;37(4):488-99.  PMID: 15256220

Bennett PV, Cuomo NL, Paul S, Tafrov ST, Sutherland BM.  Endogenous DNA damage clusters in human skin, 3-D model, and cultured skin cells.  Free Radic Biol Med. 2005 Sep 15;39(6):832-9.  PMID: 16109312

Bennett PV, Cutter NC, Sutherland BM. Split-dose exposures versus dual ion exposure in human cell neoplastic transformation. Radiat Environ Biophys. 2007 Jun;46(2):119-23.  PMID: 17256176

Bennett P, Ishchenko AA, Laval J, Paap B, Sutherland BM.  Endogenous DNA damage clusters in human hematopoietic stem and progenitor cells.  Free Radic Biol Med. 2008 Nov 1;45(9):1352-9.  PMID: 18775489

Blutt SE, Conner ME.  Kinetics of rotavirus infection in mice are not altered in a ground-based model of spaceflight.  Aviat Space Environ Med. 2004 Mar;75(3):215-9.  PMID: 15018288

Butel JS.  Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease.  Carcinogenesis. 2000 Mar;21(3):405-26.  PMID: 10688861

Butel JS, Lednicky JA.  Cell and molecular biology of simian virus 40: implications for human infections and disease.  J Natl Cancer Inst. 1999 Jan 20;91(2):119-34.  PMID: 9923853

Cano T, Murphy JC, Fox GE, Willson RC.  Separation of genomic DNA from plasmid DNA by selective renaturation with immobilized metal affinity capture.  Biotechnol Prog. 2005 Sep-Oct;21(5):1472-7.  PMID: 16209553

Cengel KA, Diffenderfer ES, Avery S, Kennedy AR, McDonough J.Using electron beam radiation to simulate the dose distribution for whole body solar particle event proton exposure.  Radiat Environ Biophys. 2010 Nov;49(4):715-21.  PMID: 20725839

Chang PY, Bakke J, Orduna J, Lin S, Doppalaudi R.  Proton-induced genetic damage in lacZ transgenic mice.  Radiat Res. 2005 Oct;164(4 Pt 2):481-6.  PMID: 16187753

Chang PY, Doppalapudi R, Bakke J, Puey A, Lin S.  Evaluation of the impact of shielding materials in radiation protection in transgenic animals.  Radiat Environ Biophys. 2007 Jun;46(2):113-8.  PMID: 17091306

Chang PY, Kanazawa N, Lutze-Mann L, Winegar R.  HZE particle radiation induced tissue-specific and p53-dependent mutagenesis in transgenic animals.  Phys Med. 2001;17 Suppl 1:189-91.  PMID: 11776257

Chinen J, Shearer WT.  Advances in asthma, allergy, and clinical immunology series 2004: Basic and clinical immunology.  J Allergy Clin Immunol. 2004 Aug;114(2):398-405.  PMID: 15316523

Coleman CB, Allen PL, Rupert M, Goulart C, Hoehn A, Stodieck LS, Hammond TG.  Novel Sfp1 transcriptional regulation of Saccharomyces cerevisiae gene expression changes during spaceflight.  Astrobiology. 2008 Dec;8(6):1071-8.  PMID: 19191537

Cucinotta FA, Dicello JF, Nikjoo H, Cherubini R.  Computational model of the modulation of gene expression following DNA damage.  Radiat Prot Dosimetry. 2002;99(1-4):85-90.  PMID: 12194368

Cucinotta FA, Schimmerling W, Wilson JW, Peterson LE, Badhwar GD, Saganti PB, Dicello JF. Space radiation cancer risks and uncertainties for Mars missions.  Radiat Res. 2001 Nov;156(5 Pt 2):682-8.  PMID: 11604093

Cucinotta FA, Wilson JW, Williams JR, Dicello JF.  Analysis of MIR-18 results for physical and biological dosimetry: radiation shielding effectiveness in LEO.  Radiation Measurements. 2000 Jun;32(3):181-91.  PMID: 11543368

Dang LH, Bettegowda C, Huso DL, Kinzler KW, Vogelstein B.  Combination bacteriolytic therapy for the treatment of experimental tumors.  Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15155-60.  PMID: 11724950

Das G, Das J, Eynott P, Zhang Y, Bothwell AL, Van Kaer L, Shi Y.  Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases.  J Exp Med. 2006 Nov 27;203(12):2603-11.  PMID: 17088432

Das J, Ren G, Zhang L, Roberts AI, Zhao X, Bothwell AL, Van Kaer L, Shi Y, Das G.  Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation.  J Exp Med. 2009 Oct 26;206(11):2407-16.  PMID: 19808254

Davis JG, Wan XS, Ware JH, Kennedy AR.  Dietary supplements reduce the cataractogenic potential of proton and HZE-particle radiation in mice.  Radiat Res. 2010 Mar;173(3):353-61.  PMID: 20199220

Devadas S, Das J, Liu C, Zhang L, Roberts AI, Pan Z, Moore PA, Das G, Shi Y.  Granzyme B is critical for T cell receptor-induced cell death of Type 2 helper T cells.  Immunity. 2006 Aug;25(2):237-47.  PMID: 16901729

DeWalt BW, Murphy JC, Fox GE, Willson RC.  Compaction agent clarification of microbial lysates.  Protein Expr Purif. 2003 Apr;28(2):220-3.  PMID: 12699684

Dicello JF.  How do we get from cell and animal data to risks for humans from space radiations?  J Radiat Res (Tokyo). 2002 Dec;43 Suppl:S1-6.  PMID: 12793722

Dicello JF.  The impact of the new biology on radiation risks in space.  Health Phys. 2003 Jul;85(1):94-102.  PMID: 12861962

Dicello JF, Christian A, Cucinotta FA, Gridley DS, Kathirithamby R, Mann J, Markham AR, Moyers MF, Novak GR, Piantadosi S, Ricart-Arbona R, Simonson DM, Strandberg JD, Vazquez M, Williams JR, Zhang Y, Zhou H, Huso D.  In vivo mammary tumourigenesis in the Sprague-Dawley rat and microdosimetric correlates.  Phys Med Biol. 2004 Aug 21;49(16):3817-30.  PMID: 15446807

Ehirchiou D, Xiong Y, Xu GW, Chen WJ , Shi YF, Zhang L.  CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation.  J Exp Med. 2007 Jul 9;204(7):1519-24.  PMID: 17562817

Encinas JM, Vazquez ME, Switzer RC, Chamberland DW, Nick H, Levine HG, Scarpa PJ, Enikolopov G, Steindler DA.  Quiescent adult neural stem cells are exceptionally sensitive to cosmic radiation.  Exp Neurol. 2008 Mar;210(1):274-9.  PMID: 18076878

Finnberg F, Wambi C, Ware JH, Kennedy AR, El-Deiry WS.  Gamma-radiation (GR) triggers a unique gene expression profile associated with cell death compared to proton radiation (PR) in mice in vivo.  Can Bio Therap. 2008 Dec;7(12):2023-33.  PMID: 19106632

Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA.  The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.  PLoS ONE. 2008 Apr 16;3(4):e2020.  PMID: 18414679

Forsman ZH, Lednicky JA, Fox GE, Willson RC, White ZS, Halvorson SJ, Wong C, Lewis AM Jr, Butel JS.  Phylogenetic analysis of polyomavirus simian virus 40 from monkeys and humans reveals genetic variation.  J Virol. 2004 Sep;78(17):9306-16.  PMID: 15308725

Georgakilas AG, Bennett PV, Wilson DM 3rd, Sutherland BM.  Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells.  Nucleic Acids Res. 2004 Oct 19;32(18):5609-20. Print 2004.  PMID: 15494449

Gordadze AV, Onunwor CW, Peng R, Poston D, Kremmer E, Ling PD.  EBNA2 amino acids 3 to 30 are required for induction of LMP-1 and immortalization maintenance.  J Virol. 2004 Apr;78(8):3919-29.  PMID: 15047808

Greeneltch KM, Haudenschild CC, Keegan AD, Shi Y.  The opioid antagonist naltrexone blocks acute endotoxic shock by inhibiting tumor necrosis factor-alpha production.  Brain Behav Immun. 2004 Sep;18(5):476-84.  PMID: 15265541

Greeneltch KM, Kelly-Welch AE, Shi Y, Keegan AD.  Chronic morphine treatment promotes specific Th2 cytokine production by murine T cells in vitro via a Fas/Fas ligand-dependent mechanism.  J Immunol. 2005 Oct 15;175(8):4999-5005.  PMID: 16210602

Guan J, Stewart J, Ware JH, Zhou Z, Donahue JJ, Kennedy AR.  Effects of dietary supplements on the space radiation-induced reduction in total antioxidant status in CBA mice.  Radiat Res. 2006 Apr;165(4):373-8.  PMID: 16579649

Guan J, Wan XS, Zhou Z, Ware J, Donahue JJ, Biaglow JE, Kennedy AR.  Effects of dietary supplements on space radiation-induced oxidative stress in Sprague-Dawley rats.  Radiat Res. 2004 Nov;162(5):572-9.  PMID: 15624312

Guida P, Vazquez ME, Otto S.  Cytotoxic effects of low- and high-LET radiation on human neuronal progenitor cells: induction of apoptosis and TP53 gene expression.  Radiat Res. 2005 Oct;164(4 Pt 2):545-51.  PMID: 16187785

Guida P, Vazquez ME.  Cytotoxic and cell cycle effects in human neuronal progenitor cells exposed to 1 GeV/n Fe ions.  Adv Space Res. 2007;39(6):1004-10.  Article abstract

Hada M, Sutherland BM.  Spectrum of complex DNA damages depends on the incident radiation.  Radiat Res. 2006 Feb;165(2):223-30.  PMID: 16435920

Jackson GW, McNichols RJ, Fox GE, Willson RC.  Universal bacterial identification by mass spectrometry of 16S ribosomal RNA cleavage products.  Int J Mass Spectrom. 2007 Mar 15;261(2-3):218-26.  Article abstract

Karim BO, Landolfi JA, Christian A, Ricart-Arbona R, Qiu W, McAlonis M, Eyabi PO, Khan KA, Dicello JF, Mann JF, Huso DL.  Estrous cycle and ovarian changes in a rat mammary carcinogenesis model after irradiation, tamoxifen chemoprevention, and aging.  Comp Med. 2003 Oct;53(5):532-8.  PMID: 14655997

Kennedy AR, Davis JG, Carlton W, Ware JH.  Effects of dietary antioxidant supplementation on the development of malignant lymphoma and other neoplastic lesions in mice exposed to proton or iron-ion radiation.  Radiat Res. 2008 Jun;169(6):615-25.  PMID: 18494549

Kennedy AR, Guan J, Ware JH.  Countermeasures against space radiation induced oxidative stress in mice.  Radiat Environ Biophys. 2007 Jun;46(2):201-3.  PMID: 17387501

Kennedy AR, Ware JH, Guan J, Donahue JJ, Biaglow JE, Zhou Z, Stewart J, Vazquez M, Wan XS.  Selenomethionine protects against adverse biological effects induced by space radiation.  Free Radic Biol Med. 2004 Jan 15;36(2):259-66.  PMID: 14744637

Kennedy AR, Zhou Z, Donahue JJ, Ware JH.  Protection against adverse biological effects induced by space radiation by the Bowman-Birk inhibitor and antioxidants.  Radiat Res. 2006 Aug;166(2):327-32.  PMID: 16881733

Keszenman DJ, Sutherland BM.  Yields of clustered DNA damage induced by charged-particle radiations of similar kinetic energy per nucleon: LET dependence in different DNA microenvironments.  Radiat Res. 2010 Aug;174(2):238-50.  PMID: 20681790

Krigsfeld GS, Sanzari JK, Kennedy AR.The effects of proton radiation on the prothrombin and partial thromboplastin times of irradiated ferrets.Int J Radiat Biol. 2012 Jan 6. [Epub ahead of print].   PMID: 22221163

Kourentzi KD, Fox GE, Willson RC.  Hybridization-responsive fluorescent DNA probes containing the adenine analog 2-aminopurine. Anal Biochem. 2003 Nov 1;322(1):124-6. 
PMID: 14705788

Kourentzi KD, Fox GE, Willson RC.  Microbial detection with low molecular weight RNA.  Curr Microbiol 43(6):444-447, 2001.  PMID: 11685514

Kourentzi KD, Fox GE, Willson RC.  Microbial identification by immunohybridization assay of artificial RNA labels.  J Microbiol Methods. 2002 May;49(3):301-6.  PMID: 11869795

Langell J, Jennings R, Clark J, Ward JB Jr.  Pharmacological agents for the prevention and treatment of toxic radiation exposure in spaceflight.  Aviat Space Environ Med. 2008 Jul;79(7):651-60.  PMID: 18619123

Larios-Sanz M, Kourentzi KD, Warmflash D, Jones J, Pierson DL, Willson RC, Fox GE. 16S rRNA beacons for bacterial monitoring during human space missions. Aviat Space Environ Med. 2007 Apr;78(4 Suppl):A43-7.  PMID: 17511298

Lednicky JA, Halvorson SJ, Butel JS.  PCR detection and DNA sequence analysis of the regulatory region of lymphotropic papovavirus in peripheral blood mononuclear cells of an immunocompromised rhesus macaque.  J Clin Microbiol. 2002 Mar;40(3):1056-9.  PMID: 11880438

Lednicky JA, Vilchez RA, Keitel WA, Visnegarwala F, White ZS, Kozinetz CA, Lewis DE, Butel JS.  Polyomavirus JCV excretion and genotype analysis in HIV-infected patients receiving highly active antiretroviral therapy.  AIDS. 2003 Apr 11;17(6):801-7.  PMID: 12660526

Lee K, Pinsky L, Andersen V, Zeitlin C, Cleghorn T, Cucinotta F, Saganti P, Atwell W, Turner R.  Helium cosmic ray flux measurements at Mars.  Radiat Meas. 2006 Oct-Nov;41(9-10):1123-5.  Article abstract

Ling PD, Lednicky JA, Keitel WA, Poston DG, White ZS, Peng R, Liu Z, Mehta SK, Pierson DL, Rooney CM, Vilchez RA, Smith EO, Butel JS.  The dynamics of herpesvirus and polyomavirus reactivation and shedding in healthy adults: a 14-month longitudinal study.  J Infect Dis. 2003 May 15;187(10):1571-80.  PMID: 12721937

Ling PD, Vilchez RA, Keitel WA, Poston DG, Peng RS, White ZS, Visnegarwala F, Lewis DE, Butel JS.  Epstein-Barr virus DNA loads in adult HIV-infected patients receiving highly active antiretroviral therapy.  Clin Infect Dis. 2003 Nov 1;37(9):1244-9.  PMID: 14557970

Murphy JC, Fox GE, Willson RC.  Enhancement of anion-exchange chromatography of DNA using compaction agents.  J Chromatogr A. 2003 Jan 17;984(2):215-21.  PMID: 12564692

Murphy JC, Fox GE, Willson RC.  RNA isolation and fractionation with compaction agent.  Anal Biochem. 2001 Aug 15;295(2):143-8.  PMID: 11488615

Murphy JC, Jewell DL, White KI, Fox GE, Willson RC.  Nucleic acid separations utilizing immobilized metal affinity chromatography.  Biotechnol Prog. 2003 May-Jun;19(3):982-6.  PMID: 12790665

Murphy JC, Wibbenmeyer JA, Fox GE, Willson RC.  Purification of plasmid DNA using selective precipitation by compaction agents.  Nature Biotechnol. 1999 Aug;17(8):822-3.  PMID: 10429254

Nance CL, Shearer WT.  SDF-1alpha regulates HIV-1-gp120-induced changes in CD79b surface expression and Ig production in activated human B cells.  Clin Immunol. 2002 Nov;105(2):208-14.  PMID: 12482395

O'Donnell PM, Aviles H, Lyte M, Sonnenfeld G.  Enhancement of in vitro growth of pathogenic bacteria by norepinephrine: importance of inoculum density and role of transferrin.  Appl Environ Microbiol. 2006 Jul;72(7):5097-9.  PMID: 16820514

O'Sullivan CE, Peng R, Cole KS, Montelaro RC, Sturgeon T, Jenson HB, Ling PD.  Epstein-Barr virus and human immunodeficiency virus serological responses and viral burdens in HIV-infected patients treated with HAART.  J Med Virol. 2002 Jul;67(3):320-6.  PMID: 12116021

Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA.  SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.  Cell. 2008 Nov 28;135(5):907-18.  PMID: 19041753

Oberdoerffer P, Sinclair DA.  The role of nuclear architecture in genomic instability and ageing.  Nat Rev Mol Cell Biol. 2007 Sep;8(9):692-702.  PMID: 17700626

Paap B, Wilson DM 3rd, Sutherland BM.  Human abasic endonuclease action on multilesion abasic clusters: Implications for radiation-induced biological damage.  Nucleic Acids Res. 2008 May;36(8):2717-27.  PMID: 18353858

Paul S, Gros L, Laval J, Sutherland BM.  Expression of the E. coli fpg protein in CHO cells lowers endogenous oxypurine clustered damage levels and decreases accumulation of endogenous Hprt mutations.  Environ Mol Mutagen. 2006 Jun;47(5):311-9.  PMID: 16518838

Pestka S, Krause CD, Sarkar D, Walter MR, Shi Y, Fisher PB.  Interleukin-10 and related cytokines and receptors.  Annu Rev Immunol. 2004;22:929-79.  PMID: 15032600

Peterson NC, Servinsky MD, Christian A, Peng Z, Qiu W, Mann J, Dicello J, Huso DL.  Tamoxifen resistance and Her2/neu expression in an aged, irradiated rat breast carcinoma model.  Carcinogenesis. 2005 Sep;26(9):1542-52.  PMID: 15860508

Pisacane VL, Kuznetz LH, Logan JS, Clark JB Wissler WH.  Thermoregulatory models of safety-for-flight issues for space operations.  Acta Astronaut. 2006 Oct;59(7):531-46.  Article abstract

Pisacane VL, Dolecek QE, Malak H, Dicello JF.  End-to-end system test for solid-state microdosimeters.  Radiat Prot Dosimetry. 2010;140(4):309-18.  PMID: 20430854

Pisacane VL, Ziegler JF, Nelson ME, Caylor M, Flake D, Heyen L, Youngborg E, Rosenfeld AB, Cucinotta F, Zaider M, Dicello JF.  MIDN: A spacecraft microdosimeter mission.  Radiat Prot Dosimetry. 2006;120(1-4):421-6.  PMID: 16785245

Powell JM, Sonnenfeld G.  The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.  J Interferon Cytokine Res. 2006 Jan;26(1):34-9.  PMID: 16426146

Reinhard MI, Cornelius I, Prokopovich D, Wroe A, Rosenfeld AB, Pisacane VL, Ziegler JF, Nelson ME, Cucinotta F, Zaider M, Dicello JF.  Response of a SOI microdosimeter to a 238PuBe neutron source.  IEEE Nuclear Science Symposium Conference Record. N3-5:68-72, 2005.  Full article

Ren G, Su J, Zhang L, Zhao X, Ling W, L'huillie A, Zhang J, Lu Y, Roberts AI, Ji W, Zhang H, Rabson AB, Shi Y.  Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression.  Stem Cells. 2009 Aug;27(8):1954-62.  PMID: 19544427

Ren G, Zhang L, Zhao X, Xu G, Zhang Y, Roberts AI, Zhao RC, Shi Y.  Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide.  Cell Stem Cell. 2008 Feb7;2(2):141-150.  PMID: 18371435

Ren G, Zhao X, Green DR, Das G, Shi YF.  Apoptotic cells induce immune tolerance through dendritic cells: critical roles of interferon-gamma and nitric oxide.  J Immunol. 2008 Sep 1;181(5):3277-84.  Article abstract

Rice L, Alfrey CP.  Modulation of red cell mass by neocytolysis in space and on earth.  Pflugers Arch. 2000;441(2-3 Suppl):R91-4.  PMID: 11200988

Rivera CA, Tcharmtchi MH, Mendoza L, Smith CW.  Endotoxemia and hepatic injury in a rodent model of hindlimb unloading.  J Appl Physiol. 2003 Oct;95(4):1656-63.  PMID: 12794033

Romero-Weaver AL, Kennedy AK. Comparison of Two Methods for the Determination of the Effects of Ionizing Radiation on Blood Cell Counts in Mice. Int J Biomed Sci. vol. 8 no. 1 March 2012.

Shearer WT.  Consequences of contamination of the spacecraft environment: immunologic consequences.  Gravit Space Biol Bull. 2001 Jun;14(2):7-14. 
PMID: 11865871

Shearer WT, Lee BN, Cron SG, Rosenblatt HM, Smith EO, Lugg DJ, Nickolls PM, Sharp RM, Rollings K, Reuben JM.  Suppression of human anti-inflammatory plasma cytokines IL-10 and IL-1RA with elevation of proinflammatory cytokine IFN-gamma during the isolation of the Antarctic winter.  J Allergy Clin Immunol. 2002 May;109(5):854-7.  PMID: 11994711

Shearer WT, Lugg DJ, Rosenblatt HM, Nickolls PM, Sharp RM, Reuben JM, Ochs HD.  Antibody responses to bacteriophage phi X-174 in human subjects exposed to the antarctic winter-over model of spaceflight.  J Allergy Clin Immunol. 2001 Jan;107(1):160-4.  PMID: 11150006

Shearer WT, Ochs HD, Lee BN, Cohen EN, Reuben JM, Cheng I, Thompson B, Butel JS, Blancher A, Abbal M, Aviles H, Sonnenfeld G.  Immune responses in adult female volunteers during the bed-rest model of spaceflight: Antibodies and cytokines.  J Allergy Clin Immunol. 2009 Apr;123(4):900-5.  PMID: 19232702

Shearer WT, Reuben JM, Mullington JM, Price NJ, Lee BN, Smith EO, Szuba MP, Van Dongen HP, Dinges DF.  Soluble tumor necrosis factor-alpha receptor 1 and interleukin-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight.  J Allergy Clin Immunol. 2001 Jan;107(1):165-70.  PMID: 11150007

Shearer WT, Zhang S, Reuben JM, Lee BN, Butel JS.  Effects of radiation and latent virus on immune responses in a space flight model, J Allergy Clin Immunol. 2005 Jun;115(6):1297-303.  PMID: 15940150

Shearer WT, Zhang S, Reuben JM, Lee BN, Butel JS.  Predictors of immune function in space flight.  Acta Astronaut. 2007 Feb-Apr;60(4-7):247-53.  Article abstract

Shi Y, Devadas S, Greeneltch KM, Yin D, Allan Mufson R, Zhou JN.  Stressed to death: implication of lymphocyte apoptosis for psychoneuroimmunology.  Brain Behav Immun. 2003 Feb;17 Suppl 1:S18-26.  PMID: 12615182

Shi Y, Liu CH, Roberts AI, Das J, Xu G, Ren G, Zhang Y, Zhang L, Yuan ZR, Tan HS, Das G, Devadas S.  Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know.  Cell Res. 2006 Feb;16(2):126-33.  PMID: 16474424

Sinclair D, Oberdoerffer P.  The ageing epigenome: Damaged beyond repair?  Ageing Res Rev. 2009 Jul;8(3):189-98.  PMID: 19439199

Singh N, Willson RC.  Boronate affinity adsorption of RNA: possible role of conformational changes.  J Chromatogr A. 1999 Apr 30;840(2):205-13.  PMID: 10343399

Smolen JE, Fossett MC, Joe Y, Prince JE, Priest E, Kanwar S, Smith CW.  Antiorthostatic suspension for 14 days does not diminish the oxidative response of murine neutrophils.  Aviat Space Environ Med. 2000 Dec;71(12):1239-47.  PMID: 11439724

Sonnenfeld, G.  Animal models for the study of the effects of spaceflight on the immune system.  Adv Space Res. 2003;32(8):1473-6. doi: 10.1016/S0273-1177(03)90383-8.  PMID: 15000088

Sonnenfeld, G.  Exploration class missions and return: Effects on the immune system.  Gravit Space Biol 19(2):45-7, 2006.

Sonnenfeld G.  The immune system in space, including Earth-based benefits of space-based research.  Curr Pharm Biotechnol. 2005 Aug;6(4):343-9.  PMID: 16101473

Sonnenfeld G.  The immune system in space and microgravity.  Med Sci Sports Exerc. 2002 Dec;34(12):2021-7.  PMID: 12471311

Sonnenfeld G.  Use of animal models for space flight physiology studies, with special focus on the immune system.  Gravit Space Biol Bull. 2005 Jun;18(2):31-5.  PMID: 16038091

Sonnenfeld, G., N. Aviles, T. Belay, M. Vance, and K. Fountain.  Stress, suspension and resistance to infection.  J Grav Physiol 9(1):199-200, 2002.

Sonnenfeld G, Aviles H, Butel JS, Shearer WT, Niesel D, Pandya U, Allen C, Ochs HD, Blancher A, Abbal M.  Bed rest and immunity.  Acta Astronaut. 2007 Feb-Apr;60(4-7):234-6.  Article abstract

Sonnenfeld G, Butel JS, Shearer WT.  Effects of the space flight environment on the immune system.  Rev Environ Health. 2003 Jan-Mar;18(1):1-17.  PMID: 12875508

Sonnenfeld G, Shearer WT.  Immune function during space flight.  Nutrition. 2002 Oct;18(10):899-903.  PMID: 12361785

Starikov D, Boney C, Medelci N, Um JW, Larios-Sanz M, Fox GE, Bensaoula A.  Experimental simulation of integrated optoelectronic sensors based on III nitrides.  J Vac Sci Technol 20:1815-1820, 2002.  Article abstract

Suman S, Datta K, Trani D, Laiakis EC, Strawn SJ, Fornace AJ Jr. Relative biological effectiveness of (12)C and (28)Si radiation in C57BL/6J mice. Radiat Environ Biophys. 2012 May 5. [Epub ahead of print]  PMID: 22585123

Sun E, Gao Y, Chen J, Roberts AI, Wang X, Chen Z, Shi Y.  Allograft tolerance induced by donor apoptotoic lymphocytes requires phagocytosis in the recipient.  Cell Death Differ. 2004 Dec;11(12):1258-64. 
PMID: 15375386

Sutherland BM, Bennett PV, Cintron NS, Guida P, Laval J.  Low levels  of endogenous  oxidative damage  cluster  levels in unirradiated viral and human DNAs.  Free Radic Biol Med. 2003 Sep 1;35(5):495-503.  PMID: 12927599

Sutherland BM, Bennett PV, Cintron-Torres N, Hada M, Trunk J, Monteleone D, Sutherland JC, Laval J, Stanislaus M, Gewirtz A.  Clustered DNA damages induced in human hematopoietic cells by low doses of ionizing radiation.  J Radiat Res (Tokyo). 2002 Dec;43 Suppl:S149-52.  PMID: 12793749

Sutherland BM, Bennett PV, Sutherland JC.  DNA damage quantitation by alkaline gel electrophoresis.  Methods Mol Biol. 2006;314:251-73.  PMID: 16673887

Sutherland BM, Cuomo NC, Bennett PV.  Induction of anchorage-independent growth in primary human cells exposed to protons or HZE ions separately or in dual exposures.  Radiat Res. Oct;164(4 Pt 2):493-6.  PMID: 16187755

Sutherland BM, Georgakilas AG, Bennett PV, Laval J, Sutherland JC.  Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis.  Mutat Res. 2003 Oct 29;531(1-2):93-107.  PMID: 14637248

Taddei PJ, Zhao Z, Borak TB.  A comparison of the measured responses of a tissue-equivalent proportional counter to high energy heavy (HZE) particles and those simulated using the Geant4 Monte Carlo code.  Radiat Meas. 2008 Oct-Nov;43(9-10):1498-1505.  PMID: 20862212

Trani D, Datta K, Doiron K, Kallakury B, Fornace AJ Jr.  Enhanced intestinal tumor multiplicity and grade in vivo after HZE exposure: Mouse models for space radiation risk estimates.  Radiat Environ Biophys. 2010 May 20. 2010 Aug;49(3):389-96  .PMID: 20490531

Tsao D, Kalogerinis P, Tabrizi I, Dingfelder M, Stewart RD, Georgakilas AG.  Induction and processing of oxidative clustered DNA lesions in 56Fe-ion-irradiated human monocytes.  Radiat Res. 2007 Jul;168(1):87-97.  PMID: 17723001

Tucker DL, Ott CM, Huff S, Fofanov Y, Pierson DL, Willson RC, Fox GE.  Characterization of Escherichia coli MG1655 grown in a low-shear modeled microgravity environment.  BMC Microbiol. 2007 Mar 7;7:15.  PMID: 17343762

Vaupel DB, Tella SR, Huso DL, Mukhin AG, Baum I, Wagner VO, Horti AG, London ED, Koren AO, Kimes AS.  Pharmacology, toxicology, and radiation dosimetry evaluation of [123I]5-I-A-85380, a radioligand for in vivo imaging of cerebral neuronal nicotinic acetylcholine receptors in humans.  Drug Dev Res 58:149-168, 2003.  Article abstract

Vilchez RA, Lednicky JA, Halvorson SJ, White ZS, Kozinetz CA, Butel JS.  Detection of polyomavirus SV40 tumor antigen DNA in AIDS-related systemic non-Hodgkin's lymphoma.  J Acquir Immune Defic Syndr. 2002 Feb 1;29(2):109-16.  PMID: 11832678

Vilchez RA, Madden CR, Kozinetz CA, Halvorson SJ, White ZS, Jorgensen JL, Finch CJ, Butel JS.  Association between simian virus 40 and non-Hodgkin lymphoma.  Lancet. 2002 Mar 9;359(9309):817-23.  PMID: 11897278

Von Gutfeld RJ, Dicello JF, McAllister SJ, Ziegler JF.  Amorphous magnetic wires for medical locator applications.  Applied Phys Letters 81:1913-1915, 2002.  Article abstract

Walling DM, Brown AL, Etienne W, Keitel WA, Ling PD.  Multiple Epstein-Barr virus infections in healthy individuals.  J Virol. 2003 Jun;77(11):6546-50.  PMID: 12743312

Walling DM, Ling PD, Gordadze AV, Montes-Walters M, Flaitz CM, Nichols CM.  Expression of Epstein-Barr virus latent genes in oral epithelium: determinants of the pathogenesis of oral hairy leukoplakia.  J Infect Dis. 2004 Jul 15;190(2):396-9.  PMID: 15216478

Wambi CO, Sanzari JK, Sayers CM, Nuth M, Zhou Z, Davis J, Finnberg N, Lewis-Wambi JS, Ware JH, El-Deiry WS, Kennedy AR.  Protective effects of dietary antioxidants on proton total-body irradiation-mediated hematopoietic cell and animal survival.  Radiat Res. 2009 Aug;172(2):175-86.  PMID: 19630522

Wambi C, Sanzari J, Wan XS, Nuth M, Davis J, Ko YH, Sayers CM, Baran M, Ware JH, Kennedy AR.  Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation.  Radiat Res. 2008 Apr;169(4):384-96.  PMID: 18363433

Wan XS, Bloch P, Ware JH, Zhou Z, Donahue JJ, Guan J, Stewart J, Kennedy AR.  Detection of oxidative stress induced by low- and high-linear energy transfer radiation in cultured human epithelial cells.  Radiat Res. 2005 Apr;163(4):364-8.  PMID: 15799690

Wan XS, Ware JH, Zhou Z, Donahue JJ, Guan J, Kennedy AR.  Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents.  Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1475-81.  PMID: 16472936

Wan XS, Zhou Z, Kennedy AR.  Adaptation of the dichlorofluorescein assay for detection of radiation-induced oxidative stress in cultured cells.  Radiat Res. 2003 Dec;160(6):622-30.  PMID: 14640785

Wan XS, Zhou Z, Ware JH, Kennedy AR.  Standardization of a fluorometric assay for measuring oxidative stress in irradiated cells.  Radiat Res. 2005 Feb;163(2):232-40.  PMID: 15658900

Wang Y, Huso D, Cahill H, Ryugo D, Nathans J.  Progressive cerebellar, auditory, and esophageal dysfunction caused by targeted disruption of the frizzled-4 gene.  J Neurosci. 2001 Jul 1;21(13):4761-71.  PMID: 11425903

Wang KX, Shi Y, Denhardt DT.  Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production.  Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14777-14782.  PMID: 17785423

Wang KX, Shi YF, Ron Y, Kazanecki CC, Denhardt DT.  Plasma osteopontin modulates chronic restraint stress-induced thymus atrophy by regulating stress hormones: inhibition by an anti-osteopontin monoclonal antibody.  J Immunol. 2009 Feb 15;182(4):2485-91.  PMID: 19201904 

Ware JH, Sanzari J, Avery S, Sayers C, Krigsfeld G, Nuth M, Wan XS, Rusek A, Kennedy AR.  Effects of proton radiation dose, dose rate and dose fractionation on hematopoietic cells in mice.  Radiat Res. 2010 Sep;174(3):325-30.  PMID: 20726731

Wei LX, Zhou JN, Roberts AI, Shi YF.  Lymphocyte reduction induced by hindlimb unloading: distinct mechanisms in the spleen and thymus.  Cell Res. 2003 Dec;13(6):465-71.  PMID: 14728803

Williams JR, Zhang Y, Zhou H, Osman M, Cha D, Kavet R, Cucinotta F, Dicello JF, Dillehay LE.  Predicting cancer risks in astronauts from animal carcinogenesis studies and cellular markers.  Mutat Res 430(2):255-269, 1999.  Article abstract

Wroe AJ, Cornelius IM, Rosenfeld AB, Pisacane VL, Ziegler JF, Nelson ME, Cucinotta F, Zaider M, Dicello JF.  Microdosimetry simulations of solar protons within a spacecraft.  IEEE Trans Nucl Sci 52(6):2591-2596, 2005.  Full article

Wroe A, Rosenfeld A, Reinhard M, Pisacane V, Ziegler J, Nelson M, Cucinotta F, Zaider M, Dicello J.  Solid state microdosimetry with heavy ions for space applications.  IEEE Trans Nucl Sci.  2007 Dec;54(6):2264-71.  Full article

Xu G, Zhang L, Ren G, Yaun Z, Zhang Y, Zhao RC, Shi YF.  Immunosuppressive properties of cloned, bone marrow mesenchymal stem cells.  Cell Res. 2007 Mar;17(3):240-8.  PMID: 17325691

Xu G, Zhang Y, Zhang U, Ren G, Shi Y.  The role of IL-6 in inhibition of lymphocyte apoptosis by mesenchymal stem cells.  Biochem Biophys Res Commun. 2007 Sep 28;361(3):745-50.  PMID: 17678624

Xu G, Zhang Y, Zhang L, Ren G, Shi Y.  Bone marrow stromal cells induce apoptosis of lymphoma cells in the presence of IFNgamma and TNF by producing nitric oxide.  Biochem Biophys Res Commun.  2008 Oct 31;375(4):666-70.  PMID: 18755151

Yoo JY, Huso DL, Nathans D, Desiderio S.  Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock.  Cell. 2002 Feb 8;108(3):331-44.  PMID: 11853668

York JM, Blevins NA, Meling DD, Peterlin MB, Gridley DS, Cengel KA, Freund GG. The biobehavioral and neuroimmune impact of low-dose ionizing radiation. Brain Behav Immun. 2011 Sep 21. PMID: 21958477

Zhang S, McNees AL, Butel JS.  Quantification of vertical transmission of Murine polyoma virus by real-time quantitative PCR.  J Gen Virol. 2005 Oct;86(Pt 10):2721-9.  
PMID: 16186225

Zhang XR, Zhang LY, Devadas S, Li L, Keegan AD, Shi YF.  Reciprocal expression of TRAIL and CD95L in Th1 and Th2 cells: role of apoptosis in T helper subset differentiation.  Cell Death Differ. 2003 Feb;10(2):203-10.  PMID: 12700648

Zhang Z, Jackson GW, Fox GE, Willson RC.  Microbial identification by mass cataloging.  BMC Bioinformatics. 2006 Mar 8;7:117.  PMID: 16524471

Zhang Z, Willson RC, Fox GE.  Identification of characteristic oligonucleotides in the 16S ribosomal RNA sequence dataset.  Bioinformatics. 2002 Feb;18(2):244-50.  PMID: 11847072

Zhang Y, Xu G, Zhang L.  Th17 cells undergo fas-mediated activation-induced cell death independent of IFN-gamma.  J Immun. 2008 Jul 1;181(1):190-6.  PMID: 18566384

Zhou G, Bennett PV, Cutter NC, Sutherland BM.  Proton-HZE-particle sequential dual-beam exposures increase anchorage-independent growth frequencies in primary human fibroblasts.  Radiat Res. 2006 Sep;166(3):488-94.  PMID: 16953667