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Research SummaryFactors associated with extended space flight might impact the body’s ability to fully defend itself against disease. Problems could include a weakened immune system and activation of dormant viruses present in the body. Radiation damage to bone marrow stem cells, which give rise to blood and immune systems, could have immediate and long-term consequences. In the close quarters of a spacecraft, a weakened immune system and increased viral activity could lead to rapid spread of infection. The Immunology, Infection and Hematology Team is studying solutions to the potential problems of weakening of the immune system, interference with wound healing, activation of dormant viruses and how radiation exposure affects the immune and blood-forming systems.
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