STUDENT INVESTIGATION 7.2
An Examination of How Your Eye Contributes to the Body's Need
to Balance: The Vestibulo-Ocular Reflex (VOR) and Nystagmus
Background
If you'll recall, all of the various signals generated by the body about
its orientation relative to the world around us, are connected and
integrated within the brain and central nervous system.
Each of our senses provides a unique signal, and when any one signal is
eliminated or changed, the brain must adapt to using
only those signals that are available.
Think of a person who is blind or deaf or even one who is paralyzed with
no feeling in their limbs. For such individuals, the brain has certainly
had to program itself to analyze and comprehend sensory information
differently from those with all of their senses intact. In fact, research
has shown that brain structures actually do differ, in both appearance
and function, among those with different sensory capabilities. In this
exercise, we are going to examine how our visual system
serves our balance system.
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| Figure 12. (a) The electromagnetic spectrum is shown in units of
Angstrom (1 Å = 10-10 meter). (b) The spectrum of visible
light comprises a very small range of wavelengths shown in units of
nanometers (1nm = 10-9 meter).
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Sight has two main functions in its interaction with the nervous system:
to receive and transform images into cognitive signals
for the brain to analyze, reflect upon, and then act on;
and to receive and transform images into spatial orientation
signals for the brain to analyze and
immediately act on without reflection. In either case,
the eyes receive energy from the electromagnetic
spectrum (Figure 12) and transform that energy into nerve
impulses that lead to the brain. Only a limited part of this spectrum can
excite the photoreceptors (rods and cones in the eye
that receive light) in the retina of the eye.
Electromagnetic energy with wavelengths between 400 and 700 nanometers
(nary) comprise visible light. It is in their role of
providing spatial information signals that the eyes work so closely with
our other senses to complete "the picture" of how our bodies are
physically oriented. We will discuss this in a moment, but let's first
look at the structure of the eyeball.
| Figure 13. The internal anatomy of
the eye. |
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Figure 13 illustrates the major parts of the eyeball. The outermost
layer of the eye is a tough coat of connective tissue called the
sclera. This can be seen externally as the white of the
eyes. The tissue of the sclera is continuous with the transparent
cornea. Light passes through the cornea to enter the
anterior chamber of the eye. Light then passes through
an opening called the pupil, within a colored muscle
called the iris. The iris regulates the diameter of the
pupil and, therefore, the amount of light entering the eye. Light that
passes through the pupil enters the lens. The lens is
responsible for refracting (deflecting or bending) light and focusing the
image that we receive. The retina, which is the inner
layer of the back portion of the eyeball, is considered the
neural layer (neural refers to neurons and the nervous
system) and it contains photoreceptors that are activated by light.
Neurons in the retina contribute fibers that are gathered together in a
region called the optic disc to exit the retina as the
optic nerve. This is also the site of entry and exit of blood vessels.
The role of the visual signal is very powerful in our balance system. In
fact, the visual and vestibular signals function particularly close
together to create our vestibulo-ocular (ocular refers
to the eye) reflex (VOR). This reflex is an effort of
the semicircular canal to compensate for the changing visual field that
arises when we move our head. Let's consider how the visual and
vestibular systems work together to help maintain balance and how a
combination of sensory information provides confirmation
of your movement.
Visual cues normally work to confirm the orientation information provided
by the vestibular, proprioceptive, tactile, and motor signals. For
example, tilt your head toward your right shoulder. The following events
will occur simultaneously:
- The image of the stationary (not moving) visual field on your retina
rotates as though your external visual field were moved
counter-clockwise, your semicircular canals signal a
clockwise movement of your head, and together they come
up with an estimate of the change in head angle.
- In addition, your eyes roll opposite to the
direction of tilt to stabilize the changing visual field. This is the
obvious part of the VOR called ocular counterrolling.
- Your otolith signals register a new head orientation with respect to
the vertical force of gravity, and this helps you confirm your
semicircular canal and visual cues. Of course, in space, this otolith
signal is not activated.
- And if all of that wasn't enough, your neck joint angle receptors and
probably your neck muscle sensors also confirm the new head position.
These events illustrate a clear case of confirming visual and vestibular
signals, leading to a strong perception of spatial
orientation. As you know, spatial orientation is affected by the
absence of gravity. We'll learn more about that subject when we review
the results of Dr. Young's space flight investigation. For now, we are
about to begin our own investigation. For this Student Investigation, we
are going to participate in two very simple activities: Part A is a
demonstration that allows you to experience the power of the VOR, and
Part B is designed to help clarify your understanding of ocular
counterrolling. Each of the two exercises should be carried out
independently by each student so that everyone will have a personal
experience with these two examples of different vestibular and visual
signal interactions. READ ALL OF THE DIRECTIONS AND QUESTIONS BEFORE
BEGINNING YOUR ACTIVITIES. This is important so that you can develop your
hypotheses before you begin the exercises and so that you will know what
questions to consider as you perform each activity. Let's get started!
Materials
Part 1: A watch with a second hand or a stopwatch for each group of two
students.
Part 2: A small mirror for each student.
Procedure
PART 1
Your Vestibulo-Ocular Reflex (VOR)
- For this demonstration, each student will individually perform two
kinds of movements (A and B) that might seem very similar, but that are
really very different. Teams of two students should work together so that
each can make sure the other is carrying out the movements correctly and
can time the movements of his or her partner.
| Figure 14. |
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- For the first movement, you will hold your hand in front of your face
and look at it from the side with your thumb about 12 to 18 inches in
front of the tip of your nose (Figure 14). Then you will begin moving
your hand back and forth, to an angle of about 10°
on either side of the nose, in front of your stationary
head. Increase the back-and-forth speed of your hand until the
image of your hand blurs. The blurring occurs as the
image of your hand begins to slip on the retina. (This is a hint that may
help you answer some of the questions!)
- For the second movement, you will be moving your
head back and forth in front of your stationary
hand, increasing the speed until your hand blurs again.
- For each of the two situations, A and B. you will determine the
frequency of movement of either your hand or your head
at the point that blurring occurs. The frequency can be
determined by counting the number of complete back and forth movements
over a 5 second period and multiplying that number by 12 to obtain a
frequency per minute.
- Develop a hypothesis before you begin your
demonstration regarding which movement ends in a blur at a lower
frequency than the other, the hand movement or the head movement, and
why.
- Begin your experiment with the help of your lab partner, who will
time the 5 second period necessary to determine movement frequency at the
point of blurred vision. During this 5 second period for each movement,
count the number of complete back-and-forth movements for both A and B.
Then calculate the frequencies and compare them. Answer the following
questions in complete sentences.
Questions
- How were the two movements different?
- Why were you able to focus on your hand longer during one movement
than the other?
- What were the primary sensory signals that were used in each movement?
- Hypothesize about what you would expect if you carried out this
experiment in space and why.
- Combine the answers to Questions #2 and #3 to state what you have
learned about the vestibulo-ocular reflex.
PART 2
Recognizing the Effect of Ocular Counterrolling
- For this demonstration, each student will perform two kinds of
movements (A and B) that, as in the previous exercise, might seem very
similar but that use very different vestibular and visual signals.
(That's a hint for you to be able to answer one of the questions at the
end.) Teams of two students should work together so that one student can
verify that the other student is carrying out the movements correctly and
can record the other student's observations. Read the following
descriptions before you begin this exercise.
- For the first movement, you will hold a mirror in front
of your face so that you can see your eyes very clearly. You will then
begin to slowly tilt your head toward your right shoulder. While tilting,
carefully observe your eyeball. You will be looki ng for any kind of
movement. If you're unable to detect eye movement, tilt your head a little
bit faster, but not too much for you not to see the eyes. Verbally
describe your eye movement to your lab partner so that your observations
can be recorded.
- For the second movement, you will again hold a mirror
in front of your face so that you can see your eyes clearly. This time,
however, you will be lying on your back. You will begin
to slowly tilt your head toward your right shoulder again while observing
your eyes. Verbally describe your eye movement to your lab partner so that
your observations can be recorded.
- Before you begin any part of this exercise, develop an hypothesis
about what you expect the eye to do in each movement situation and why.
Then begin your experiment based on your teacher's instructions. Compare
any differences in eye movement that you
observe. Finally, answer the following questions.
Questions
- Why was there a difference in eye movement when you tilted your
head while in a vertical position versus when you tilted your head while
in a horizontal position? (The hint is in the question!)
- What are the rotational axes (pitch, yaw, or roll) that you
participate in for each of the two different movements, and which sensory
organs are at work to detect movements in each of the two instances?
- What is ocular counterrolling and why does it occur?
- What does this demonstration indicate about the vestibulo-ocular reflex?
- Hypothesize about what you would expect if you carried out this
experiment in space and why.
- How is this demonstration in Part 2 similar to and different from the
demonstration in Part 1 of this Student Investigation?
Let's move on to examine the results of Dr. Young's space flight investigation!
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