Human Physiology in Space Outline

Spacelab	Cardio- vascular System	Blood Components	Fluid Regulation	Muscular System	Skeletal System	Human Sensory & Balance System
Focus 1	Focus 2	Focus 3	Focus 4	Focus 5	Focus 6	Focus 7

Introduction:Humans In Space Overview Environment Environmental Challenges Facing Humans In Space The Atmosphere Radiation Gravity Body Changes How The Human Body Changes In Space

	Focus 1:Space as a Laboratory for the Life Sciences Legacy The Legacy of Space Life Sciences Research Space Shuttle Tight Control of the Space Shuttle/Spacelab Environment Meeting the Personal Needs of the Human in Space The Spacelab Life Sciences Missions: SLS-1 and SLS-2

Focus 2: Examining the Effects of Space Flight on the Heart, Lungs, and Blood Vessels Earth Physiology Introduction The Heart and the Circulation Blood Pressure, Flow, and Resistance Factors that Influence Arterial Blood Pressure Central Venous Pressure The Respiratory System Space Physiology Student Investigations (SI) Your Perspective The Scientific Method SI1: Demonstration of How Cardiac Output and Exercise Are Related SI2: "Puffy-Head, Bird-Legs" Syndrome Simulation SI3: Affect on Cardiac Output with Headward Fluid Shift Conclusions of SI1-SI3 SI4: Defining and Graphically Interpreting Respiratory Measurements SI5: Determination of Personal Respiratory Measurement Profile Space Flight Investigations Introduction Central Venous Pressure Heart Chamber Size and Volume Static Leg Volume Cardiovascular Function During a Stand Test Cardiovascular Function During Exercise "Congratulations!" Speaking of Space Focus Conclusion

Focus 3: Examining the Effects of Space Flight on the Blood and its Components Earth Physiology The Major Components of Blood Hematocrit Red Blood Cell Mass Erythropoiesis Space Physiology Student Investigations (SI) Your Perspective SI1: How do Hematocrit Values Vary Among Populations? SI2: The Dilution Method for Determining Fluid Volumes SI3: Determining the Efficiency of RBC Production in the Bone Marrow Space Flight Investigations The Space Flight Investigation Measurements to Understand Quantitative Changes in the Major Blood Components The RBC Faucet Measurement of Erythropoietin Levels and Circulating RBC Production and Survival Congratulations! Focus Conclusion Speaking of Space

Focus 4: Examining the Effects of Space Flight on the Fluid Regulating Systems of the Body Earth Physiology Introduction The Kidney The Formation of Urine: Figuration, Reabsorption, and Secretion Control of Urine Volume Space Physiology Student Investigations (SI) Your Perspective SI1: The Kidney and Homeostasis SI2: Performing a Serial Dilution SI3: Cardiovascular Blood, and Renal/ Endocrine Responses to the Fluid Shift Space Flight Investigation The Space Flight Investigation Renal Function Measurements Hormonal and Electrolyte Changes in Space Focus Conclusion Speaking of Space

Focus 5: Examining the Effects of Space Flight on the Muscles Earth Physiology Introduction Skeletal Muscle Muscle Filaments - The Engine of the Muscle Muscle Energetics Animal Experimentation Space Physiology Student Investigations (SI) Your Perspective SI1: Muscle Energy Systems Are Used for Different Physical Activities SI2: Performing Physical Activities to Predict Energy Metabolism SI3: Type I Muscle Fiber Distribution in the Quadricep Muscle Groups Space Flight Investigations The Space Flight Investigation Muscle Mass Measurements and Type I/Type II Muscle Fiber Distribution in Rats Changes in the Endurance Level of Rat Muscle Congratulations! Speaking of Space Focus Conclusion

Focus 6: Examining the Effects of Space Flight on the Skeletal System Earth Physiology Introduction Bone Development and Structure Bone Function Space Physiology Student Investigations (SI) Your Perspective SI1: Predicting Height from the Length of Limb Bones SI2: The Influence of Applied Forces on Different Materials Space Flight Investigations The Space Flight Investigation Measurement of Body Mass and Body Length in Rats Changes in the Mineralization Rate and Strength of Rat Bones "Congratulations!" Focus Conclusion Speaking of Space

Focus 7: Examining the Effects of Space Flight on the Human Sensory and Balance System Earth Physiology Introduction Structure and Function of the Sensory and Balance Organs Uniting the Senses Metabolism and Protection of our Nervous System Space Physiology Student Investigations (SI) Your Perspective SI1: The Rotating Chair Experiment SI2: Examination of the Eyes' Contributions to the Body's Need for Balance Space Flight Investigations The Space Flight Investigation Changes in the Visual Components of Balance During Space Flight Awareness of Position and Posture Congratulations! Speaking of Space Focus Conclusion

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